Comparison of Platelet Indices in ST Elevation Myocardial Infarction and Non-ST Elevation Myocardial Infarction Patients At Advent Hospital Bandar Lampung

Wahyu Setianing Budi; Hidayat; Neno Fitriyani Hasbie; Devita Febriani Putri

doi:10.30872/

Penulis

Wahyu Setianing Budi Universitas Malahayati Penulis
Hidayat Universitas Malahayati Penulis https://orcid.org/0009-0007-0445-1537 (tidak diautentikasi)
Neno Fitriyani Hasbie Universitas Malahayati Penulis https://orcid.org/0000-0002-7245-7400 (tidak diautentikasi)
Devita Febriani Putri Universitas Malahayati Penulis https://orcid.org/0000-0002-4602-736X (tidak diautentikasi)

DOI:

https://doi.org/10.30872/

Kata Kunci:

Warfarin, fibrilasi atrium, stroke berulang, perubahan dosis, indeks massa tubuh

Abstrak

Sindrom Koroner Akut (SKA) merupakan salah satu penyebab utama morbiditas dan mortalitas akibat penyakit kardiovaskular. Aktivasi trombosit berperan penting dalam proses aterotrombosis yang mendasari terjadinya ST-Elevation Myocardial Infarction (STEMI) dan Non-ST-Elevation Myocardial Infarction (NSTEMI). Penelitian ini bertujuan menganalisis perbedaan nilai indeks trombosit antara pasien STEMI dan NSTEMI di Rumah Sakit Advent Bandar Lampung. Penelitian menggunakan desain observasional analitik dengan pendekatan retrospektif terhadap 104 pasien yang memenuhi kriteria inklusi. Data diperoleh dari rekam medis dan dianalisis menggunakan uji Chi-square, Mann–Whitney, dan Independent Samples t-test. Hasil penelitian menunjukkan bahwa jenis kelamin berhubungan signifikan dengan tipe infark miokard (p=0,018), sedangkan usia pasien NSTEMI lebih tinggi dibandingkan STEMI (p=0,014). Median jumlah trombosit pada kelompok STEMI lebih tinggi dibandingkan NSTEMI, yaitu 416.500 sel/mm³ dan 310.000 sel/mm³ (p<0,001). Rerata MPV, PDW, dan PCT pada kelompok STEMI juga lebih tinggi dibandingkan NSTEMI dengan nilai p masing-masing 0,015; 0,001; dan 0,007. Disimpulkan bahwa jumlah trombosit, Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), dan Plateletcrit (PCT) berbeda secara signifikan antara pasien STEMI dan NSTEMI serta berpotensi menjadi parameter hematologi tambahan dalam evaluasi pasien SKA.

Biografi Penulis

Wahyu Setianing Budi, Universitas Malahayati

Department of Medicine, Faculty of Medicine, Universitas Malahayati, Bandar Lampung, Indonesia
Hidayat, Universitas Malahayati

Department of Clinical Pathology, Faculty of Medicine, Universitas Malahayati, Bandar Lampung, Indonesia
Neno Fitriyani Hasbie, Universitas Malahayati

Public Health Program, Faculty of Medicine, Universitas Malahayati, Bandar Lampung, Indonesia
Devita Febriani Putri, Universitas Malahayati

Department of Parasitology, Faculty of Medicine, Universitas Malahayati, Bandar Lampung, Indonesia

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