Karakteristik Fisik Morfologi, pH, dan Waktu Alir Serbuk Serat Ampas Kelapa sebagai Bahan Pengisi Sediaan Farmasi

Physical Characteristics Morphology, pH, and Flow Time of Coconut Pulp Fiber Powder as a Filling Material for Pharmaceutical Preparations

Penulis

  • Amatullah Syarifah Jurusan Farmasi, Fakultas Ilmu-Ilmu Kesehatan, Universitas Jenderal Soedirman Penulis
  • Tuti Sri Suhesti Jurusan Farmasi, Fakultas Ilmu-Ilmu Kesehatan, Universitas Jenderal Soedirman Penulis
  • Rehana Jurusan Farmasi, Fakultas Ilmu-Ilmu Kesehatan, Universitas Jenderal Soedirman Penulis

Kata Kunci:

Ampas kelapa, Bahan pengisi sediaan farmasi, Karakteristik fisik morfologi, pH, Waktu alir serbuk serat

Abstrak

Utilization of coconut pulp fiber is still low so that it can be used in the pharmaceutical industry. This study aims to determine the physical characteristics of morphology, pH, and flow time of coconut pulp fiber powder as a filler in pharmaceutical preparations. The procedure of this research was started by making coconut pulp fiber powder, morphological characteristic test, pH test, and flow time test. The results of this study are: (1) Morphological characteristics test, coconut pulp fiber powder has a slightly yellowish white color, tasteless, odorless, and roughness of 426-600 m which means it is in accordance with pharmaceutical grade; (2) the pH of the powder is 6.43 which means it is close to neutral; and (3) the flow time test showed a result of 4.73 grams/second, which means the powder can flow well. In conclusion, coconut pulp powder can be used as a filler in pharmaceutical preparations.

Referensi

Direktorat Jenderal Perkebunan, Statistik perkebunan indonesia 2015-2017: Kelapa (coconut). Jakarta: Kementerian Pertanian, 2017.

W. Miskiyah, I., Mulyawati, & Haliza, “’Pemanfaatan ampas kelapa limbah pengolahan minyak kelapa murni menjadi pakan,” in Seminar Nasional Teknologi Peternakan dan Vertenier, 2006, pp. 881–883.

M. F. Putri, “Kandungan gizi dan sifat fisik tepung ampas kelapa sebagai bahan pangan sumber serat,” TEKNOBUGA J. Teknol. Busana dan Boga, vol. 1, no. 1, pp. 32–43, 2014.

Wulandari, I. G. Yudha, and L. Santoso, “Kajian pemanfaatan tepung ampas kelapa sebagai campuran pakan untuk ikan lele dumbo, clarias gariepinus (Burchell, 1822),” e-Jurnal Rekayasa dan Teknol. Budid. Perair., vol. 6, no. 2, pp. 713–718, 2018.

M. R. Arumugam, B. Johson, and K. Eagappan, “Dietary fiber isolate from coconut flakes-a function food,” Int. J. Pharm., vol. 25, no. 2, pp. 261–267, 2014.

M. Cespi et al., “Evaluation of Citrus Fibers as a Tablet Excipient,” AAPS PharmSciTech, vol. 15, no. 2, pp. pages279–286, 2014.

R. Yulvianti, M., Widya, E., Tarsono, M., & Alfian, “Pemanfaatan Ampas Kelapa sebagai Bahan Baku Tepung Kelapa Tinggi Serat dengan Metode Freeze Drying,” J. Integr. Proses, vol. 5, no. 2, pp. 1-1–107, 2015.

A. Santoso, “Serat Pangan (Dietary Fiber) dan Manfaatnya Bagi Kesehatan,” Magistra, vol. 23, no. 78, pp. 35–40, 2015.

E. Anwar, Eksipien dalam Sediaan Farmasi. Jakarta: Dian Rakyat, 2012.

R. C. Rowe, P. J. Sheskey, and M. E. Quinn, “Handbook of pharmaceutical excipients,” in Handbook of Pharmaceutical Excipients, 6th ed., Washington D.C: Pharmaceutical Press and American Pharmacists Association, 2009.

L. Hadisoewignyo and A. Fudholi, Sediaan solida. Yogyakarta: Pustaka Pelajar, 2013.

M. E. Aulton, Pharmaceutics the science of dosage form design. London: Churchill Livingstone, 1988.

P. D. Pawar, P. M. Arane, H. B. Saindane, S. G. Talele, G. Shinde, and G. Chaudhari, “Review on pharmaceutical excipients,” Am. J. Pharm. Heal. Res., vol. 3, no. 2, pp. 30–50, 2015.

Unduhan

Diterbitkan

2022-06-30

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Cara Mengutip

[1]
A. Syarifah, T. S. Suhesti, dan Rehana, “Karakteristik Fisik Morfologi, pH, dan Waktu Alir Serbuk Serat Ampas Kelapa sebagai Bahan Pengisi Sediaan Farmasi: Physical Characteristics Morphology, pH, and Flow Time of Coconut Pulp Fiber Powder as a Filling Material for Pharmaceutical Preparations”, J. Sains. Kes, vol. 4, no. 3, hlm. 331–336, Jun 2022, Diakses: Sep 21, 2026. Tersedia pada: https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/577

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