Identifikasi Senyawa Aktif Ekstrak Daun Pulutan (Urena lobata L) dengan GC-MS

Identification of Active Compound in Pulutan (Urena lobata L) Leaf extract using GC-MS

Authors

  • Ummu Farah Fadillah Fakultas Teknologi Pertanian, IPB, Bogor, Jawa Barat Author
  • Erliza Hambali Fakultas Teknologi Pertanian, IPB, Bogor, Jawa Barat Author
  • Muslich Muslich Fakultas Teknologi Pertanian, IPB, Bogor, Jawa Barat Author

Keywords:

Daun Pulutan (Urena lobata L), GC-MS, Senyawa Aktif

Abstract

Daun pulutan (Urena lobata Linn) merupakan salah satu jenis tumbuhan yang sudah sejak lama dimanfaatkan oleh masyarakat sebagai obat untuk berbagai macam penyakit. Penelitian ini dilakukan untuk mengetahui komponen senyawa aktif yang terdapat di dalam ekstrak etanol daun pulutan dengan menggunakan GC-MS. Hasil identifikasi menunjukkan bahwa ekstrak etanol 50% daun pulutan mengandung 6 senyawa yang didominasi oleh n-Hexadecanoic acid dan Stigmasta-3,5-diene. Sedangkan ekstrak etanol 70% terdapat 18 senyawa yang didominasi oleh 4h-pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-, 2-methoxy-4-vinylphenol, phenol, 2,6-dimethoxy-, dann-hexadecanoic acid.

References

Biofarmaka Research Center IPB. 2015. Herbal plants collection of biopharmaca conservation and cultivation station. [diunduh 2018 Des 12]. Tersedia pada : http://biofarmaka.ipb.ac.id/biofarmaka/2015/BCCS%20Herbal%20Plants%20Collections%20Temulawak.pdf.

Ali MS, Kazi OF, Aziz ARM, Hossain MA. 2013. Antioxidant and cytotoxic activities of methanol extract of Urena lobata(L) leaves. The Pharma Innovation –Journal. 2:9-14.

Shruti M, Srinivas B, Alfiha M. 2016. Exploring the pharmacognostic characteristics and antimicrobial potential of Urena lobata Linn. International Research Journal of Pharmacy. 7 (11) : 31-37. doi: 10.7897/2230-8407.0711124.

Gao XL, Ying L, Jie W, Xiao-Yan L, Kai Z, Yi-Na H, Hong G, Bo G, Zheng-Jun X. 2015. Discovery of a potent anti-yeast triterpenoid saponin, clematoside-s from Urena lobata L. International Journal of Molecular Sciences. 16 : 4731-4743. doi:10.3390/ijms16034731

Fagbohun ED, Asare RR, Egbebi AO. 2012. Chemical composition and antimicrobial activities of Urena lobataL.(Malvaceae). Journal of Medicinal Plants Research. pp. 2256-2260. doi: 10.5897/JMPR10.233.

Pieme CA, Ngoganga J, Marietta C. 2012. In vitro anti proliferative and anti-oxidant activities of methanol extracts of Urena lobata and Viscum album against breast cancer cell lines. Toxicological and Environmental Chemistry. doi: 10.1080/02772248.2012.674135.

Su C, Bowen Q, Juan W, Ning D, Yun W, Xiao-Ping S, Zhi-Xiang Z, Xiao L, Xiao-Hui W, Jiao Z, Peng-Fei T, She-Po S. 2018. Megastigmane glycosides from Urena lobata. Fitoterapia. 127:123-128. Doi :10.1016/j.fitote.2018.02.017.

Sharifi N, Shabnam M, Massoud A. 2017. Comparison of different methods in quercetin extraction from leaves of Rapharus sativus L. Pharmaceutical Sciences59-65 doi:10.15171/PS.2017.09.

Ardiyanti A, Kusnadi J. 2014. Ekstraksi antibakteri dari daun berenuk (Crescentia cujete Linn.) menggunakan metode ultrasonic. Jurnal Pangan dan Agroindustri. p.28-35.

Novitasari MR, Lizma F, Risna A, Agung R, Rolan R. 2016. Analisis GC-MS Senyawa Aktif Antioksidan Fraksi Etil Asetat Daun Libo (Ficus variegata Blume.). Jurnal Sains dan Kesehatan. Vol 1. No 5.p-ISSN: 2303-0267.

[BTBRD] Balai Teknologi Bahan Bakar dan Rekayasa Disain. GC MS [Internet]. [diunduh tanggal 16 Mei 2019]. Tersedia pada : https://btbrd.bppt.go.id/index.php/gcms

Tiwari P, Bimlesh K, Mandeep K, Gurpreet K, Harleen K. 2011. Phytochemical screening and Extraction: A Review. Internationale Pharmaceutica Sciencia. Vol 1. Issue 1.

Ghaidaa JM, Mohammad JA, Imad HH. 2016. Anti-bacterial, Antifungal Activity and Chemical Analysis of Punica grantanum (Pomegranate peel) Using GC-MS and FTIR Spectroscopy. International Journal of Pharmacognosy and Phytochemical Research. 8(3); 480-494. ISSN: 0975-4873.

Sogandi G, Darma WST, Jannah R. 2019.Potential of Antibacterial Compounds from Sweet Root Extract (Glycyrrhiza glabra L) on Bacillus cereus. Jurnal Kimia Sains Dan Aplikasi, 22(4), 105.doi:10.14710/jksa.22.4.105-111.

Conforti F, Statti GA,Menichini F. 2007. Chemical and biological variability of hot pepper fruits (Capsicum annuum var. acuminatum L.) in relation to maturity stage. Food Chem. 102:1096–1104

Ban JO, Hwang IG, Kim TM, Hwang BY, Lee US, Jeong HS, Yoon YW, Kim DJ, Ban JTHJ. 2007. Anti-proliferate and pro-apoptotic effects 0f 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pryranone through inaction of NF-kB in Human Colon Cancer Cells. Arch Pharm ResVol. 30 No. 11:1455-1463. doi:10.1007/BF02977371.

Jeong JB, Se CH, Hyung JJ, Jin SK. 2011. Anti-inflammatory Effect of 2-Methoxy-4-Vinylphenol via the Suppression of NF-κB and MAPK Activation, and Acetylation of Histone H3. Arch Pharm ResVol 34, No 12, 2109-2116. doi 10.1007/s12272-011-1214-9.

Yang JF, Yang CH, Liang MT, Gao ZJ, Wu YW, Chuang LY. 2016. Chemical Composition, Antioxidant, and Antibacterial Activity of Wood Vinegar from Litchi chinensis Molecules 21, 1150; doi:10.3390/molecules21091150

Downloads

Published

2024-11-14

Issue

Vol. 2 No. 3 (2020): J. Sains Kes.

Section

Articles

How to Cite

[1]
U. F. Fadillah, E. Hambali, and Muslich Muslich, “Identifikasi Senyawa Aktif Ekstrak Daun Pulutan (Urena lobata L) dengan GC-MS: Identification of Active Compound in Pulutan (Urena lobata L) Leaf extract using GC-MS”, J. Sains. Kes, vol. 2, no. 3, pp. 217–221, Nov. 2024, Accessed: Nov. 25, 2025. [Online]. Available: http://jsk.ff.unmul.ac.id/index.php/JSK/article/view/148

Similar Articles

71-80 of 231

You may also start an advanced similarity search for this article.