Analysis of the Effect of Spraying Frequency and Working Period on Acetylcholinesterase Levels in Corn Farming Using Pesticides

Muawanah Muawanah; Nurul Azhima; Muh. Aswar; Muh. Rifo Rianto; Sabaniah Indjar Gama

doi:10.30872/

Authors

Muawanah Muawanah Politeknik Muhammadiyah Makassar Author
Nurul Azhima Politeknik Muhammadiyah Makassar Author
Muh. Aswar Politeknik Muhammadiyah Makassar Author
Muh. Rifo Rianto Politeknik Muhammadiyah Makassar Author
Sabaniah Indjar Gama Mulawarman University Author

DOI:

https://doi.org/10.30872/

Keywords:

pesticide, spraying frequency, duration of work, acethylcholinesterase level

Abstract

Pesticides are hazardous chemicals that are used to control pests that threaten humans and play a role in supporting agricultural and plantation productivity as well as eradicating disease vectors. With the increasing use of pesticides, the risk of exposure for farmers will rise and may effect nervous system function by inhibiting activity of the enzyme acetylcholinesterase thereby reducing acetylcholinesterase levels. Acetylcholinesterase is an enzyme involved in the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid. The objective of this study was to determine the effect of spraying frequency and duration of work on acetylcholinesterase in corn farmers who use pesticides. This study employed a photometric method with a laboratory observational design and used purposive sampling. The analysis of effects was conducted using the chi-square test. Of the 20 farmers samples, 18 had normal acetylcholinesterase levels ranging from 5.523 to 11.151 U/L while 2 samples showed elevated levels ranging from 13.572 – 14.453 U/L compared to normal acetylcholinesterase levels of 4.620 – 11.500 U/L for men and 3.930 – 10.800 U/L for women. The results of the test examining the effect of spraying frequency and duration of work on acetylcholinesterase levels yielded p-values of 0.456 and 0.329 U/L. Conclusion: There was no significant effect of spraying frequency or duration of work on acetylcholinesterase levels.

Author Biographies

Muawanah Muawanah, Politeknik Muhammadiyah Makassar

Department of Medical Laboratory Technology, Muhammadiyah Polytechnic of Makassar, Indonesia
Nurul Azhima, Politeknik Muhammadiyah Makassar

Department of Medical Laboratory Technology, Muhammadiyah Polytechnic of Makassar, Indonesia
Muh. Aswar, Politeknik Muhammadiyah Makassar

Department of Medical Laboratory Technology, Muhammadiyah Polytechnic of Makassar, Indonesia
Muh. Rifo Rianto, Politeknik Muhammadiyah Makassar

Department of Medical Laboratory Technology, Muhammadiyah Polytechnic of Makassar, Indonesia
Sabaniah Indjar Gama, Mulawarman University

Department of Pharmacy, Mulawarman University, Samarinda, Indonesia

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