Aktivitas Antiulseratif Berbagai Tanaman Herbal dan Prospek Masa Depan Sebagai Tanaman Budidaya

Anti-ulceritis Activity of Various Herbal Plants and Future Prospects as Cultivated Plants

Authors

  • Hafizh Zahra Institut Pertanian Bogor Author
  • Rosa Berlina Haridas Institut Pertanian Bogor Author
  • Gusnia Meilin Gholam Institut Pertanian Bogor Author
  • Aprijal Ghiyas Setiawan Institut Pertanian Bogor Author

Keywords:

Gastroprotektif, Herbal, Tinjauan Sistematik, Ulkus Peptikum, Senyawa Metabolit

Abstract

Penyakit ulkus peptikum (PUD) merupakan salah satu gangguan gastrointestinal yang umum terjadi pada individu berusia 20-50 tahun dengan 1081 kasus kematian (0.08%) di Indonesia tahun 2021. Faktor risiko utama PUD antara lain penggunaan obat antiinflamasi nonsteroid (NSAID), infeksi Helicobacter pylori, penyalahgunaan alkohol, merokok, dan stres fisik. Dewasa kini, terapi PUD beralih ke penggunaan metabolit sekunder tanaman herbal guna menyaingi pengobatan alofatik yang berefek samping. Melalui tinjauan sistemik ini, beberapa metabolit tanaman herbal bertanggung jawab atas efek gastroprotektif, penghambatan neurotransmiter tertentu, inhibisi pompa proton atau efek antiinflamasi lain. Penelusuran literatur dilakukan melalui basis data besar (PubMed, Science Direct, Semantic Scholar, Springer Link, SAGE, dan Google Scholar) dengan kata kunci yang berasosiasi dengan PUD. Fokus data yang ditelaah antara lain jenis tanaman, kelompok senyawa metabolit, dosis in vivo, mekanisme aksi metabolit, dan metode analisis.

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Published

2024-11-14

Issue

Vol. 4 No. 3 (2022): J. Sains Kes.

Section

Review

How to Cite

Aktivitas Antiulseratif Berbagai Tanaman Herbal dan Prospek Masa Depan Sebagai Tanaman Budidaya: Anti-ulceritis Activity of Various Herbal Plants and Future Prospects as Cultivated Plants. (2024). Jurnal Sains Dan Kesehatan, 4(3), 343-353. https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/579