Cystic Fibrosis: Review

Authors

  • I Gusti Agung Ari Kusuma Yana Magister Farmasi Fakultas Farmasi Universitas Surabaya, Surabaya Author

Keywords:

Cystic fibrosis, Mokus, Saluran Pernafasan, Mutasi Gen

Abstract

Cystic fibrosis (CF) merupakan penyakit genetik autosomal yang mematikan yang diturunkan terutama oleh populasi ras putih atau kaukasia. Kondisi ini disebabkan oleh mutasi gen CFTR terutama CFTR Phe508del. Jika terjadi kerusakan atau kesalahan CFTR maka fungsi normal akan terganggu dan berdampak klinis pada organ yang lain atau multiorgan. Komplikasi seperti pada pankreas, hati, saluran pencernaan, tulang, genital, serta saluran pernafasan yang terutama dapat menyebabkan kematian paling banyak pada penderita cystic fibrosis. Kondisi malabsorpsi, inflamasi, infeksi dan obstruksi paru-paru kronis merupakan tanda-tanda dari cystic fibrosis. Terapi untuk cystic fibrosis sebatas pada pembersihan mokus saluran pernafasan, pencegahan infeksi yang presisten dengan antibiotik, meningkatkan kesehatan fisik dan gizi pasien

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Published

2024-11-14

Issue

Vol. 3 No. 1 (2021): J. Sains Kes.

Section

Review

How to Cite

Cystic Fibrosis: Review. (2024). Jurnal Sains Dan Kesehatan, 3(1), 79-87. https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/189

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