Insidensi dan Karakteristik Karsinoma Hepatoseluler di RSUD Abdul Wahab Sjahranie Samarinda

Authors

  • Dinda Aprilistya Puri Universitas Mulawarman Author
  • Sinta Murti Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Mulawarman Author
  • Yudanti Riastiti Laboratorium Radiologi Fakultas Kedokteran Universitas Mulawarman Author

Keywords:

Karsinoma hepatoseluler, insidensi, karakteristik, survival rate

Abstract

Karsinoma hepatoseluler (KHS) merupakan kanker hati primer yang terjadi akibat tumbuhnya sel hepatosit secara abnormal. KHS menduduki peringkat kelima insidensi kasus kanker terbanyak dan urutan keempat penyebab kematian akibat kanker di dunia tahun 2018. Pasien KHS memiliki prognosis yang buruk dan survival rate yang rendah. Penelitian ini bertujuan untuk mengetahui insidensi dan karakteristik karsinoma hepatoseluler di RSUD Abdul Wahab Sjahranie Samarinda. Penelitian ini merupakan penelitian deskriptif retrospektif. Data yang digunakan dalam penelitian ini diperoleh dari data rekam medik pasien periode Februari 2017-Februari 2020. Hasil penelitian ini terdapat 206 pasien KHS. Dari 206 pasien 82,5% adalah laki-laki dengan kelompok usia tertinggi 50-59 tahun (33,5%), hepatitis B (62,6%) menjadi faktor risiko terbanyak, 60,7% pasien mengalami peningkatan level AFP, 43,7% menunjukkan klasifikasi Child-Pugh B, 22,3% menunjukkan stadium BCLC B, terapi paling banyak diberikan adalah terapi tanpa intervensi (93,2%). Survival rate secara signifikan dipengaruhi oleh klasifikasi Child-Pugh (p=0,017) dan stadium BCLC (p=0,037), tetapi survival rate tidak dipengaruhi oleh modalitas terapi (p=0,92). Berdasarkan penelitian ini dapat disimpulkan bahwa insidensi KHS pada 3 tahun terakhir masih tinggi, pasien KHS laki-laki lebih banyak daripada perempuan, kelompok usia tertinggi adalah kelompok usia 50-59 tahun, faktor risiko terbanyak adalah hepatitis B, pasien KHS lebih banyak mengalami peningkatan level AFP, klasifikasi Child-Pugh terbanyak adalah Child-Pugh B, stadium dengan jumlah terbanyak adalah stadium B, dan survival rate 1 tahun dipengaruhi oleh klasifikasi Child-Pugh dan stadium BCLC.  

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Published

2024-11-14

Issue

Vol. 3 No. 2 (2021): J. Sains Kes.

Section

Articles

How to Cite

[1]
D. A. Puri, S. . Murti, and Y. . Riastiti, “Insidensi dan Karakteristik Karsinoma Hepatoseluler di RSUD Abdul Wahab Sjahranie Samarinda”, J. Sains. Kes, vol. 3, no. 2, pp. 158–164, Nov. 2024, Accessed: Dec. 15, 2025. [Online]. Available: https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/206

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