Aplikasi Farmakologis dan Formulasi Jamu sebagai Bahan Aktif dalam Produk Nutrasetikal dan Makanan Fungsional: Tinjauan Komprehensif: Pharmacological Applications and Jamu Formulations as Active Ingredients in Nutraceutical and Functional Food Products: A Comprehensive Review

Nanny  Djaya; Hadi Kuncoro; Daniel Tjen; Jaya Suprana; Fajar Prasetya

doi:10.30872/jsk.v6i2.840

Aplikasi Farmakologis dan Formulasi Jamu sebagai Bahan Aktif dalam Produk Nutrasetikal dan Makanan Fungsional: Tinjauan Komprehensif

Pharmacological Applications and Jamu Formulations as Active Ingredients in Nutraceutical and Functional Food Products: A Comprehensive Review

Authors

Nanny Djaya Rumah Sakit Pendidikan & Riset Atma Jaya, Fakultas Kedokteran, Kesehatan Masyarakat & Gizi, Universitas Katolik Atma Jaya, Jakarta, Indonesia Author
Hadi Kuncoro Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia; 1Rumah Sakit Pendidikan & Riset Atma Jaya; Dewan Jamu Indonesia Author
Daniel Tjen Dewan Jamu Indonesia Author
Jaya Suprana Dewan Jamu Indonesia Author
Fajar Prasetya Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia; Rumah Sakit Pendidikan & Riset Atma Jaya; Dewan Jamu Indonesia Author https://orcid.org/0000-0002-1020-0423

DOI:

https://doi.org/10.30872/jsk.v6i2.840

Keywords:

Jamu, nutrasetikal, makanan fungsional, metabolit primer, metabolit sekunder, senyawa bioaktif, formulasi

Abstract

Jamu, sebagai warisan pengobatan tradisional Indonesia, telah digunakan secara turun-temurun untuk menjaga kesehatan dan mengobati berbagai penyakit. Seiring meningkatnya kesadaran global akan manfaat produk alami, potensi jamu kini dieksplorasi secara ekstensif dalam pengembangan produk nutrasetikal dan makanan fungsional modern. Artikel review komprehensif ini bertujuan untuk mengkaji secara mendalam aplikasi farmakologis dari bahan-bahan jamu, mengidentifikasi senyawa bioaktif, serta menganalisis tantangan dan inovasi dalam formulasi produk-produk tersebut. Kami mengulas peran ganda dari metabolit primer dan sekunder, dengan fokus pada senyawa bioaktif utama seperti kurkuminoid, andrografolida, dan gingerol, yang terbukti memiliki aktivitas antiinflamasi, antioksidan, dan imunomodulator. Selain itu, kami menganalisis tantangan formulasi kritis seperti stabilitas, bioavailabilitas, dan isu organoleptik. Solusi teknologi canggih seperti mikroenkapsulasi, nanoteknologi (nanoemulsi, liposom), dan penggunaan bioenhancers juga dibahas secara rinci. Kami menyimpulkan bahwa integrasi jamu ke dalam produk modern memerlukan pendekatan ilmiah yang ketat, termasuk standardisasi ekstrak, validasi klinis yang transparan, dan regulasi yang jelas, untuk menjamin keamanan dan khasiatnya. Artikel ini memberikan landasan ilmiah yang kuat untuk penelitian dan pengembangan jamu di masa depan

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Published

2025-11-10

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Vol. 6 No. 2 (2025)

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Review

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N. . Djaya, H. Kuncoro, D. Tjen, J. Suprana, and F. Prasetya, “Aplikasi Farmakologis dan Formulasi Jamu sebagai Bahan Aktif dalam Produk Nutrasetikal dan Makanan Fungsional: Tinjauan Komprehensif: Pharmacological Applications and Jamu Formulations as Active Ingredients in Nutraceutical and Functional Food Products: A Comprehensive Review”, J. Sains. Kes, vol. 6, no. 2, pp. 101–115, Nov. 2025, doi: 10.30872/jsk.v6i2.840.

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