Senyawa Alkaloid Furokuinolin dari Kulit Batang Zanthoxylum acanthopodium DC

Authors

  • Tjitjik Srie Tjahjandarie Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia Author https://orcid.org/0000-0003-0894-9803
  • Alfiah Nur Irza Gunawan Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia Author
  • Ratih Dewi Saputri Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia Author https://orcid.org/0000-0002-5982-8983
  • Mulyadi Tanjung Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia Author https://orcid.org/0000-0002-8252-6692

Keywords:

Zanthoxylum acanthopodium DC., diktammin, skimmianin, antikanker

Abstract

Dua senyawa alkaloid furokuinolin, diktammin (1) dan skimmianin (2) telah berhasil diisolasi dari kulit batang Zanthoxylum acanthopodium DC. Penentuan struktur kedua senyawa alkaloid ditetapkan berdasarkan analisis spektrum UV, IR, MS,1D dan 2D NMR. Uji aktivitasantikanker senyawa 1–2 terhadap sel murine leukemia P-388 memperlihatkan nilai IC 50 10,41 dan 4,85 μg/ml.

References

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Published

2019-12-31

Issue

Vol. 2 No. 2 (2019): J. Sains Kes.

Section

Articles

How to Cite

Senyawa Alkaloid Furokuinolin dari Kulit Batang Zanthoxylum acanthopodium DC. (2019). Jurnal Sains Dan Kesehatan, 2(2). https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/52