Review: Aktivitas Imunostimulan dari Famili Malvaceae

Review: Immunostimulant Activity from Malvaceae Family

Authors

  • Syifa Rizkia Khoerunisa Prodi S1 Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam. Universitas Garut Author
  • Atun Qowiyyah Prodi S1 Farmasi, Fakultas Matematika dan Imu Pengetahuan Alam. Universitas Garut, Tarogong, Garut, Jawa Barat, Indonesia, 44151 Author
  • Sitti Fatimah Putri Hasyul Prodi S1 Farmasi, Fakultas Matematika dan Imu Pengetahuan Alam. Universitas Garut, Tarogong, Garut, Jawa Barat, Indonesia, 44151 Author

Keywords:

Aktivitas imunosimulan, Imunostimulan, Malvaceae, Respon imun, Sistem imun

Abstract

Pandemi COVID-19 hingga saat ini masih mewabah di seluruh dunia, termasuk Indonesia. Kasus positif COVID-19 per-tanggal 22 juli 2021, di Indonesia sebanyak 3.033.339 jiwa dengan angka kematian 79.032 jiwa. Imunostimulan merupakan zat yang dapat meningkatkan daya tahan tubuh terhadap infeksi, termasuk untuk menangkal infeksi virus corona. Imunostimulan dapat berasal dari bahan sintetis atau bahan alam.  Tanaman famili Malvaceae sering digunakan sebagai obat tradisional untuk mengobati diare, batuk, dan menjaga daya tahan tubuh. Review artikel ini bertujuan untuk memberikan informasi mengenai famili Malvaceae yang memiliki aktivitas imunostimulan. Metode yang digunakan dalam review artikel yaitu studi literatur secara online melalui berbagai database seperti Google Scholar, PubMed, dan ScienceDirect. Hasil review menunjukan tanaman Abelmoschus esculentus, Abelmoschus manihot L., Hibiscus sabdarifa L., Hibiscus rosa-sinensis L., Sterculia villosa Roxb., Luehea divaricata Mart. & Zucc., dan Sida cordifolia, menunjukan aktivitas imunostimulan. Spesies paling berpotensi sebagai agen imunostimulan, yaitu Sterculia villosa Roxb., karena mampu meningkatkan berbagai mediator dan sitokin pada sistem imun, serta telah dilakukan pengujian secara in vitro, in vivo, dan in silico terhadap senyawa lupeol dari Sterculia villosa Roxb., yang mampu meningkatkan daya tahan tubuh terhadap infeksi.

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Published

2022-10-31

Issue

Vol. 4 No. 5 (2022): J. Sains Kes.

Section

Review

How to Cite

Review: Aktivitas Imunostimulan dari Famili Malvaceae: Review: Immunostimulant Activity from Malvaceae Family. (2022). Jurnal Sains Dan Kesehatan, 4(5), 523–533. https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/550

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