Gambaran Faktor Risiko Periprocedural Myocardial Injury pada Pasien Yang Menjalani IKP Elektif Di RSUD AWS Samarinda Periode Mei-Oktober 2019

Penulis

  • Khairun Nisa Program Studi Kedokteran Universitas Mulawarman Penulis https://orcid.org/0000-0002-4738-4406
  • Muhammad Furqon Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Mulawarman Penulis
  • Hary Nugroho Laboratorium Anatomi Fakultas Kedokteran Universitas Mulawarman Penulis

Kata Kunci:

pMI, faktor resiko, PCI, CAD

Abstrak

Periprocedural myocardial injury adalah salah satu komplikasi setelah intervensi koroner perkutan elektif yang sering terjadi, dan memiliki hubungan dengan peningkatan mortalitas. Beberapa faktor risiko telah dikaitkan dengan kejadian periprocedural myocardial injury. Tujuan penelitian adalah untuk mengetahui gambaran faktor risiko periprocedural myocardial injury yang terbagi menjadi faktor risiko terkait pasien, lesi dan prosedur. Penelitian dilakukan dengan desain penelitian cohort prospectif dan pengambilan sampel secara purposive sampling pada bulan Maret-Oktober 2019. Jumlah sampel sebanyak 38 orang. Hasil penelitian didapatkan sampel yang mengalami periprocedural myocardial injury sebanyak 31,6%. Adapun gambaran faktor risiko pada penelitian ini menunjukkan bahwa pasien dengan diabetes melitus tipe-2 lebih sering mengalami periprocedural myocardial injury. Adapun untuk faktor risiko lainnya, tidak didapatkan proporsi periprocedural myocardial injury yang lebih besar dari proporsi non-periprocedural myocardial injury pada pasien dengan faktor risiko tersebut. Namun, didapatkan peningkatan proporsi kejadian periprocedural myocardial injury seiring dengan bertambahnya jumlah arteri koroner yang memiliki lesi aterosklerosis.

Referensi

[1] Popma, J. J., & Bhatt, D. L. (2012). Percutaneus Coronary Intervention. Dalam R. O. Eugene Braunwald, Braunwald's Heart Disease : A textbook of cardiovascular medicine (hal. 1284-1285). Philadelphia: Elsevier.

[2] Zeitouni, M., Silvain, J., Guedeney, P., Kerneis, M., Yan, Y., Overtchouk, P., et al. (2018). Periproceduralmyocardial infarction and injury in elective coronary stenting. European Heart Journal, 39(13),1100-1109.

[3] Cuculi, F., Lim, C. C., & Banning, A. P. (2010). Periprocedural myocardial injury during elective percutaneous coronary intervention: is it important and how can it be prevented? Heart, 96 (10), 736-740.

[4] Tricoci, P. (2016). Consensus or Controversy? : Evolution of Criteria for Myocardial Infarction After Percutaneous Coronary Intervention. Clinical Chemistry, 63(1), 82-90.

[5] J.Tietze, K. (2012). Review of Laboratory and Diagnostic Test. Dalam K. J.Tietze, Clinical Skills for Pharmacists (hal. 91). St. Louis: Elsevier Mosby.

[6] Babu, G. G., Walker, J. M., Yellon, D. M., & Hausenloy, D. J. (2011). Peri-procedural myocardial injury during percutaneous coronary intervention:an important target for cardioprotection. European Heart Journal, 32(1), 23-31.

[7] Lansky, A. J., & Stone, G. W. (2010). Periprocedural Myocardial Infarction: Prevalence, Prognosis, and Prevention. Circulation: Cardiovascular Interventions, 3(6), 602-610.

[8] Haggag, Y., Saleh, M., Khaled, M., & Elhadidy, A. (2017). Impact of periprocedural myocardial necrosis on short term clinical outcome. The Egyptian Journal of Critical Care Medicine, 5(2), 69-72.

[9] Herrmann, J. (2005). Peri-procedural myocardial injury: 2005 update. European Heart Journal, 26(23), 2493-519.

[10] Idris, H., Lo, S., Shugman, I. M., Saad, Y., & Hopkins, A. P. (2017). Varying Definitions for Periprocedural Myocardial Infarction Alter Event Rates and Prognostic Implications. American Heart Assosiation, 3(6), 1-3.

[11] Park, D.-W., Kim, Y.-H., Yun, S.-C., Ahn, J.-M., Lee, J.-Y., Kim, W.-J., et al. (2013). Frequency, causes, predictors, and clinical significance of peri-procedural myocardial infarction following percutaneus coronary intervention. Europan Heart Journal, 34(22), 1662-1669

[12] Moolman, J. A. (2006). Unravelling the cardioprotective mechanism of action of estrogens. Cardiovascular Research, 69(4), 777-780.

[13] Rodgers, J. L., Jones, J., Bolleddu, S. I., Vanthenapalli, S., Rodgers, L. E., Shah, K., et al. (2019). Cardiovascular Risks Associated with Gender and Aging. Journal of Cardiovascular Development and Disease, 6(2), 2-3.

[14] Jerkic, H., Tomislav Letilovic, Stipinovic, M., Pocanic, D., Catic, J., & Knotek, M. (2016). Association of chronic kidney disease with periprocedural myocardial injury after elective stent implantation. Medicine, 95(45), 4-5

[15] Zhong, Z., Liu, J., Zhang, Q., Zhong, W., Li, B., Li, C., et al. (2017). Relationship Between Preoperative Low-Density Lipoprotein Cholesterol and Periprocedural Myocardial Injury in Patients Following Elective Percutaneous Coronary Intervention in Southern China. Medical Science Monitor, 24, 4154-4161.

[16] Chen, Z.-W., Yang, H.-B., Chen, Y.-H., Ma, J.-Y., Qian, J.-Y., & Ge, J.-B. (2017). Impact of multivessel therapy to the risk of periprocedural myocardial injury after elective coronary intervention: exploratory study. BMC Cardiovascular Disorders, 17(1), 69.

[17] Galinanes, M., & Fowler, A. G. (2004). Role of clinical pathologies in myocardial injury following ischaemia and reperfusion. Cardiovascular Research, 61(3), 512-521.

[18] Li, X.-L., Li, J.-J., Guo, Y.-L., Zhu, C.-G., Xu, R.- X., Li, S., et al. (2014). Relationship of Glycated Hemoglobin Levels with Myocardial Injury following Elective Percutaneous Coronary Intervention in Patients with Type 2 Diabetes Mellitus. Plos One, 9(7), 5.

[19] Rezende, P. C., Hueb, W., Rahmi, R. M., Scudeler, T. L., Azevedo, D. F., Garzillo, C. L., et al. (2017). Myocardial injury in diabetic patients with multivessel coronary artery disease after revascularization interventions. Diabetology & Metabolic Syndrome, 9, 92.

[20] Verdoia, M., Barbieri, L., Schaffer, A., Cassetti, E., Giovine, G. D., Nardin, M., et al. (2015). Impact of Diabetes mellitus on periprocedural myocardial infarction in patients undergoing coronary stent implantation. Diabetes Metabolism Research and Review, 31(1), 85-92.

[21] Anfossi, G., Russo, I., & Trovati, M. (2008). Resistance to Aspirin and Thienopyridines in Diabetes Mellitus and Metabolic Syndrome. Current Vascular Pharmacology, 6(4), 313-28.

[22] Loeb, H. S., & Liu, J. C. (2010). Frequency, Risk Factors, and Effect on Long-Term Survival of Increased Troponin I Following Uncomplicated Elective Percutaneous Coronary Intervention. Clinical Cardiology, 33(12), 40-44.

[23] Michalak, M., Huczek, Z., Filipiak, K. J., Roik, M., Kochman, J., & Opolski, G. (2013). Periprocedural myocardial damage during percutaneous coronary intervention:a point-of-care platelet testing and intravascular ultrasound/virtual histology study. Kardiologia Polska, 71(4), 325-333.

[24] Uetani, T., Amano, T., Ando, H., Yokoi, K., Arai, K., Kato, M., et al. (2008). The correlation between lipid volume in the target lesion,measured by integrated backscatter intravascular ultrasound, and post-procedural myocardial infarction in patients with elective stent implantation. European Heart Journal, 29(14), 1714-1720.

[25] Mandal, M., Rahman, M., Akanda, M., Ullah, M., & Kar, N. (2014). Influence of Stent Length on Peri–Procedural Myocardial Injury after Percutaneous Coronary Intervention. Cardiovascular Journal, 6(2), 147.

[26] Buturak, A., Degirmencioglu, A., Surgit, O., Demir, A. R., Karakurt, H., Erturk, M., et al.

(2016). Rise of serum troponin levels following uncomplicated elective percutaneous coronary interventions in patients without clinical and procedural signs suggestive of myocardial necrosis. Advances in Interventional Cardiology, 12(1), 41-48.

[27] Safarian, H., Alidoosti1, M., Shafiee, A., Salarifar, M., Poorhosseini, H., & Nematipour, E. (2014). The SYNTAX Score Can Predict Major Adverse Cardiac Events Following Percutaneous Coronary Intervention. Heart Views, 15(4), 99-105.

[28] Yüceler, Z., Kantarcı, M., Tanboğa, İ. H., Sade, R., Kızrak, Y., Pirimoğlu, B., et al. (2016). Coronary lesion complexity assessed by SYNTAX score in 256-slice dual-source MDCT angiography. Diagnostic & Interventional Radiology, 22(4), 334–340.

Unduhan

Diterbitkan

2024-11-14

Terbitan

Vol 2 No 4 (2020): J. Sains Kes.

Bagian

Articles

Cara Mengutip

Gambaran Faktor Risiko Periprocedural Myocardial Injury pada Pasien Yang Menjalani IKP Elektif Di RSUD AWS Samarinda Periode Mei-Oktober 2019. (2024). Jurnal Sains Dan Kesehatan, 2(4), 324-330. https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/194

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