Pengaruh Konsentrasi PVA terhadap Stabilitas dan Aktivitas Antioksidan Masker Peel Off Ekstrak Kulit Jengkol (Archidendron pauciflorum (Benth.) Nielsen)

Authors

  • Zahrina Hanny Nabila Program Studi S1 Farmasi, STIKes Karya Putra Bangsa Author
  • Ary Kristijono Program Studi S1 Farmasi, STIKes Karya Putra Bangsa Author
  • Dara Pranidya Tilarso Program Studi S1 Farmasi, STIKes Karya Putra Bangsa Author

Keywords:

ekstrak kulit jengkol, IC50, masker peel off, PVA

Abstract

Jengkol skin (Archidendron pauciflorum (Benth.) Nielsen) has antioxidant activity because it contains flavonoid compounds, saponins, and alkaloids, so jengkol skin can be used as a facial treatment. The peel off mask preparation was chosen because is one type of cosmetic that is easy to use because it utilizes the ability to release the film layer when applied to the skin so that it can increase comfort in use and is expected to increase the antioxidant activity of jengkol skin extract. Components of masks such as PVA (Polyvinyl Alcohol) which act as filming agents, affect the physical properties of the mask, because it is the material underlying the peel off mask. A stability test needs to be carried out to ensure the durability of the mask during storage. This study aims to determine the stability and antioxidant activity of peel off masks of jengkol skin from various concentrations of PVA. The method used is maceration with 70% ethanol solvent. PVA was used with concentrations of 6%, 8% and 10%. The physical properties test includes organoleptic test, pH test, homogenity test, adhesion test, dispersion test, dry time test, and viscosity test. The antioxidant test of peel off mask preparations was carried out by DPPH method (1,1 Difenyl-2-picrylhydrazil). Based on the results of the study, it was obtained that the peel off mask preparation was stable for a maximum of 21 days of storage. Formula with a PVA concentration of 10% is the formula that has the best physical properties during storage but is the most unstable formula because there are more white lumps than other formulas on the 28th day. The IC50 values ??were 420.9 ?g/mL, 397.4 ?g/mL and 434.1 ?g/mL

References

[1] Tranggono, RI dan Latifah F, 2007, Buku Pegangan Ilmu Pengetahuan Kosmetik. Jakarta : PT. Gramedia Pustaka Utama, 11, 90-93

[2] Rizal, Mohamad, Yusransyah dan Sofi Nurmay Setiani, 2016, Uji Aktivitas Antidiare Ekstrak Etanol 70% Kulit Buah Jengkol (Archidendron Pauciflorum (Benth.) I.C.Nielsen) terhadap Mencit Jantan yang Diinduksi Oleum Ricini, Jurnal Ilmiah Manuntung, Tangerang : Universitas Mata’ul Anwar Pandeglang. Vol. 2(2), 131-136.

[3] Rokhati, Nur; Bambang Pramudono, L. Nyoman Widiasa dan Heru Susanto, 2012, Karakterisasi Film Komposit Alginat dan Kitosan. Reaktor, Semarang : Universitas Diponegoro, Vol. 14, No. 2.

[4] Pratiwi, Liza, 2018, Formulasi dan Aktivitas Antioksidan Masker Wajah Gel Peel Off Ekstrak Metanol Buah Pepaya (Carica Papaya L.), Pharmacy Medical Journal, Pontianak : Universitas Tanjungpuri, Vol. 1, No. 2.

[5] Dirjen POM, 1985, Cara Pembuatan Simplisia, Jakarta : Direktorat Jendral Pengawas Obat dan Makanan, 2, 4-22.

[6] Depkes RI. 2000, Parameter Standar Umum Ekstrak Tumbuhan Obat, Jakarta : Departemen Kesehatan Republik Indonesia, 10-11.

[7] Harborne, J.B. 2006, Metode Fitokimia Penuntun Cara Modern Menganalisis Tumbuhan, edisi kedua, Bandung : Institut Teknologi Bandung, 61.

[8] Setyani, Wahyuning et al, 2016, Pemanfaatan Ekstrak Terstandrisasi Daun Som Jawa (Talinum paniculatum (Jacq.) Gaertn) dalam Sediaan Krim Antibakteri Staphylococcus Aureus, Jurnal Farmasi Sains dan Komunitas, Vol. 13, No. 1.

[9] Anggraeni, Yuni; Sabrina dan Putri Laras Pertiwi, 2012, Formulasi Gel Masker Peel Off Ekstrak Air Bongkahan Gambir (Uncaria gambir roxb.) dengan Basis Kitosan dan Polivinil Alkohol, BIOLINK, Jakarta : Fakultas Kedokteran dan Ilmu Kesehatan UIN Syarif Hidayatullah.

[10] Anief, M,. 1997, Ilmu Meracik Obat, Yogyakarta : Gadjah Mada University Press. 10-17.

[11] Ulaen, Selfie P.J., Banne, Yos Suatan & Ririn A., 2012, Pembuatan Salep Anti Jerawat dari Ekstrak Rimpang Temulawak (Curcuma xanthorriza Roxb), Jurnal Ilmiah Farmasi, Vol. 3(2), 45-49.

[12] Tunjungsari, Dila; T.N. Saifullah Sulaiman dan Rima Munawaroh, 2012, Formulation Gel Containing Ethanolic Extract of Mahkota Dewa Fruits (Phaleria macrocarpa (Scheff.) Boerl.) with Carbomer, Naskah Publikasi, Surakarta : Universitas Muhammadiyah Surakarta.

[13] Wahyudin, Munifah; Ajeng Kurniati dan Gusti Ayu Putu Aridewi, 2018, Pengaruh Konsenrasi Carbopol 940 Terhadap Stabilitas Fisik Sediaan Masker Ekstrak Buah Mengkudu (Morinda citrifolia L.) Sebagai Anti Jerawat, JF FIK UINAM, Vol. 6, No. 1.

[14] Sumiyati dan Mandike Ginting, 2017, Formulasi Masker Gel Peel Off dari Kulit Buah Pisang Kepok (Musa Paradisiaca L.), Jurnal Dunia Farmasi, Institut Kesehatan Helvetia. Vol. 1, No. 3.

[15] Zulkarnain, A. Karim, 2013, Stabilitas Fisik Sediaan O/W dan W/O Ekstrak Buah Mahkota Dewa sebagai Tabir Surya dan Uji Iritasi Primer pada Kelinci, Traditional Medicine Journal, Yogyakarta : Universitas Gadjah Mada Press, Vol. 18, No. 3.

[16] Mitayani, Gigih, 2010, Uji Aktivitas Antioksidan Ekstrak Etanol dan Ekstrak Air Buah Pala (Myristica fragan houtt) dengan Metode DPPH (1,1-difenil-2-pikrilhidrazil), Skripsi, Universitas Negeri Semarang.

Downloads

Published

2024-11-14

Issue

Vol. 2 No. 4 (2020): J. Sains Kes.

Section

Articles

How to Cite

[1]
Z. H. Nabila, A. Kristijono, and D. P. Tilarso, “Pengaruh Konsentrasi PVA terhadap Stabilitas dan Aktivitas Antioksidan Masker Peel Off Ekstrak Kulit Jengkol (Archidendron pauciflorum (Benth.) Nielsen)”, J. Sains. Kes, vol. 2, no. 4, pp. 480–490, Nov. 2024, Accessed: Dec. 17, 2025. [Online]. Available: https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/272

Similar Articles

41-50 of 225

You may also start an advanced similarity search for this article.