Aplikasi Farmakologis dan Formulasi Jamu sebagai Bahan Aktif dalam Produk Nutrasetikal dan Makanan Fungsional: Tinjauan Komprehensif
Pharmacological Applications and Jamu Formulations as Active Ingredients in Nutraceutical and Functional Food Products: A Comprehensive Review
DOI:
https://doi.org/10.30872/jsk.v6i2.840Keywords:
Jamu, nutrasetikal, makanan fungsional, metabolit primer, metabolit sekunder, senyawa bioaktif, formulasiAbstract
References
[1] Acri, A., Creese, H., & Griffiths, A. (2011). The Oldest Text in Southeast Asia? The Inscription of Sukabumi and the Dating of the Kakawin Ramayana. Journal of Southeast Asian Studies, 42(1), 1-28.
[2] Adnan, M., et al. (2018). Salak fruit (Salacca zalacca) extract for the development of antioxidant functional food. Journal of Functional Foods, 48, 120-128.
[3] Aggarwal, B. B., & Shishodia, S. (2006). Molecular targets of curcumin, a naturally occurring anti-inflammatory agent. Current Drug Targets, 7(5), 453-463.
[4] Al-Farsi, M., & Lee, C. Y. (2008). Nutritional and functional properties of dates: A review. Critical Reviews in Food Science and Nutrition, 48(10), 877–887.
[5] Al Makmun, et al. (2014). Serat Primbon Jampi Jawi: Tinjauan Filologi dan Etnomedisin. Jurnal Ilmu Budaya, 2(1), 10-25.
[6] Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007). Bioavailability of curcumin: Problems and promises. Molecular Pharmaceutics, 4(6), 807–818. https://doi.org/10.1021/mp070011c
[7] Bansal, N., et al. (2018). Mineral clay and its applications in health and medicine. Journal of Pharmaceutical Sciences, 107(1), 1-15.
[8] Benavente-García, O., Castillo, J., Rivas, R. A., & Ortuño, A. (1997). The role of citrus flavonoids in health: A review of their antioxidant properties. Journal of Agricultural and Food Chemistry, 45(12), 4349-4357.
[9] Boyer, J., & Liu, R. H. (2004). Apple phytochemicals and their health benefits. Nutrition Journal, 3(1), 5. https://doi.org/10.1186/1475-2891-3-5
[10] British Library. (2019). Javanese Manuscripts. Diakses dari https://www.bl.uk.
[11] Calder, P. C. (2015). Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance. Biochemical Society Transactions, 43(6), 1161-1165. https://doi.org/10.1042/BST20150172
[12] Chrubasik, S., Pittler, M. H., & Roufogalis, B. D. (2005). Zingiberis rhizoma: A comprehensive review on the ginger compound. Phytomedicine, 12(9), 684–686. https://doi.org/10.1016/j.phymed.2005.04.004
[13] Cunha, S. C., & Fernandes, J. O. (2018). Food Bioactive Peptides: Biological activity and health benefits. Journal of Functional Foods, 48, 642–653.
[14] Deshmukh, B. S., Gite, V. V., & Nikam, S. M. (2022). Microencapsulation of curcumin: A review. Journal of Drug Delivery and Therapeutics, 12(4), 211-218. https://doi.org/10.22270/jddt.v12i4.5492
[15] Djamaluddin, M., et al. (2021). Kajian Etnomedisin Terhadap Serat Centhini. Jurnal Etnobotani Indonesia, 12(1), 45-56.
[16] Estiasih, T., et al. (2025). The Javanese jamu in its sociocultural, philosophical and historical context. Trends in Food Science & Technology.
[17] Fahey, J. W. (2005). Moringa oleifera: A review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Trees for Life Journal, 1(5), 1-15.
[18] Garg, S., Singh, J., & Kaur, S. (2015). A review on standardization of herbal drugs. Journal of Pharmacognosy and Phytochemistry, 4(1), 1-5.
[19] Ghadiri, M., Mokhtar, N., Arulselvan, P., & Shariff, F. (2013). Bioactive components and clinical applications of edible bird's nest. Jurnal Bioteknologi & Biokimia, 2(1), 40–51.
[20] Gunawan, F. (2023). Aksara Jawa dan Manuskrip Kuna. Jurnal Budaya, 15(2), 1-10.
[21] Guo, C., et al. (2014). Sialic acid-rich glycopeptides from edible bird's nest enhance immune function. Journal of Functional Foods, 11, 237-246.
[22] Handayani, L., & Nurhanifa, N. (2020). Tinjauan pemanfaatan teknologi nanoenkapsulasi kurkuminoid pada jamu. Jurnal Farmasi Sains dan Komunitas, 17(1), 12–21.
[23] Hartanti, D., et al. (2020). A review of Indonesian herbal medicine for COVID-19 prevention and treatment: The role of jamu. Journal of Health Science, 10(2), 1-8.
[24] Hewlings, S. J., & Kalman, D. S. (2017). Curcumin: A review of its effects on human health. Foods, 6(10), 92. https://doi.org/10.3390/foods6100092
[25] Ibrahim, S. I., et al. (2019). Regulation of nutraceuticals in Indonesia: The role of Badan Pengawas Obat dan Makanan (BPOM). Journal of Regulatory Science, 42(1), 32-41.
[26] Jalil, M. (2019). Javanese traditional medicine: A study on Serat Primbon Jampi Jawi. International Conference on Social Science and Humanities.
[27] Jatimprov. (2016). Serat Centhini: Ensiklopedi Budaya Jawa Abad ke-19. Diakses dari http://www.jatimprov.go.id.
[28] Kagoshima University. (2002). Jamu: The Ancient Art of Javanese Herbal Medicine. Diakses dari http://www.kagoshima-u.ac.jp.
[29] Kementrian Pendidikan dan Kebudayaan. (2022). Warisan Budaya Takbenda: Jamu. Diakses dari https://warisanbudaya.kemdikbud.go.id.
[30] Kruegel, A. C., & Grundmann, O. (2017). The kratom problem: New insights into pharmacology and toxicology. Drug and Alcohol Dependence, 181, 1-7. https://doi.org/10.1016/j.drugalcdep.2017.07.030
[31] Kurmalasari, N. A., et al. (2024). Malay medical manuscripts and traditional healing practices: A review. Jurnal Sains Kesihatan.
[32] Lao, L., Ren, J., & Lao, K. (2012). Acupuncture and traditional Chinese medicine for the treatment of pain: A systematic review. Pain, 153(1), 1-10. https://doi.org/10.1016/j.pain.2011.08.016
[33] Lantz, R. C., et al. (2007). The effect of gingerol on the production of inflammatory mediators from human monocytes. Phytomedicine, 14(2-3), 123-129. https://doi.org/10.1016/j.phymed.2006.01.002
[34] Lankes, K., et al. (2021). Bananas as a source of dopamine and serotonin. Food Chemistry, 356, 129487.
[35] McClements, D. J. (2011). Edible nanoemulsions: Fabrication, properties, and functional performance. Soft Matter, 7(6), 2297–2316.
[36] Messina, M. (2016). Soy and Health: A Review. Nutrients, 8(11), 754. https://doi.org/10.3390/nu8110754
[37] Mufidah, L. A., et al. (2021). Chemical composition and sensory evaluation of "beras kencur" as a functional beverage. International Journal of Food Science and Technology, 56(7), 3350-3358.
[38] Mustofa, A., Suseno, S., & Susanti, R. (2017). The effect of snakehead fish (Channa striata) extract on wound healing and albumin levels in post-operative patients: A systematic review. Malaysian Journal of Medicine and Health Sciences, 13(1), 57–63.
[39] Nur Syukriah, Z., et al. (2017). A review of the health benefits of rambutan (Nephelium lappaceum L.). Food Science and Technology Research, 23(1), 1-8. https://doi.org/10.3136/fstr.23.1
[40] Okhuarobo, A., et al. (2014). A review of the phytochemistry and pharmacology of Andrographis paniculata. Asian Pacific Journal of Tropical Biomedicine, 4(1), 1–13. https://doi.org/10.1016/S2221-1691(14)60262-1
[41] Oktavianus, B., Sitorus, P., & Sinaga, N. (2018). Efek imunomodulator ekstrak daun sambiloto (Andrographis paniculata) terhadap tikus putih. Jurnal Farmasi Indonesia, 15(2), 170–177.
[42] Patwardhan, B., Warude, D., Pushpangadan, P., & Bhatt, N. (2005). Ayurveda and traditional Chinese medicine: A comparison of their theoretical foundations and clinical practices. The Journal of Alternative and Complementary Medicine, 11(6), 1145–1152. https://doi.org/10.1089/acm.2005.11.1145
[43] Prasetya, F. (2024). Dasar Farmakologi, Kimia Medisinal, & Jamulogi. Elex Media Komputindo, Kompas Gramedia. ISBN.9786230056697.
[44] Pudjiastuti, D. (2011). Serat Primbon Jampi Jawi: Teks dan Terjemahan. Balai Pelestarian Nilai Budaya Yogyakarta.
[45] Purwaningsih, E. (2013). Kajian Etimologi Jamu. Simposium Nasional Jamu, Jakarta.
[46] Saini, R. K., et al. (2014). Potential of Moringa oleifera as a functional food: A review of its nutritional, pharmacological, and industrial applications. Journal of Functional Foods, 6(1), 12–28.
[47] Sari, I. P., & Pratiwi, Y. (2019). Review: Peningkatan bioavailabilitas kurkumin dengan sistem liposom. Jurnal Ilmu Farmasi dan Farmasi Klinik, 16(1), 30–38.
[48] Sarifudin, N. A., et al. (2017). A review of the antioxidant properties of stingless bee honey. Journal of Apicultural Research, 56(4), 415-427.
[49] Semwal, R. B., Semwal, D. K., Combrinck, S., Viljoen, A. M., & Ojha, S. K. (2015). Ginger (Zingiber officinale Roscoe): A review on its chemical composition and bioactive compounds. Industrial Crops and Products, 70, 482–491. https://doi.org/10.1016/j.indcrop.2015.02.023
[50] Sharma, D., et al. (2017). Mung bean (Vigna radiata) and its bioactive compounds: A review on their nutritional and therapeutic potential. Food Research International, 102, 192-205.
[51] Shoba, G., et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica, 64(4), 353–356.
[52] Sholikhah, U. (2016). Jamu as a traditional herbal medicine in Indonesia: A review on its regulation and standardization. Journal of Pharmaceutical Research International, 12(4), 1-10.
[53] Siddappa, B. D., Sharma, S., & Kumar, H. (2008). A review on the health benefits of mangiferin. Journal of Ethnopharmacology, 115(3), 363-380.
[54] Subramanian, M., Srividhya, N., & Narendhirakannan, R. T. (2020). Current status and future perspectives of nano-nutraceuticals in therapeutics. Journal of Pharmaceutical Analysis, 10(3), 209-224.
[55] Sumarni, N., Nurjazuli, J., & Sudarso, S. (2019). Ethnomedicine of traditional herbal medicine in Semarang City, Central Java, Indonesia. Journal of Ethnopharmacology, 243, 112112.
[56] Suryani, D., et al. (2025). The role of traditional jamu handlers in maintaining the quality and safety of traditional medicine in Indonesia. Journal of Community Health, 20(1), 1-8.
[57] Susilo, P. S. (2022). Pengobatan Tradisional Jawa dalam Serat Centhini. Jurnal Kebudayaan, 19(2), 1-15.
[58] Suswardany, D., Khasanah, S., & Kurniawan, A. (2017). The use of traditional herbal medicine for malaria treatment in Indonesia: A systematic review. International Journal of Environmental Research and Public Health, 14(11), 1335.
[59] Tandfonline. (2023). Jamu: Indonesian traditional herbal medicine. Diakses dari https://www.tandfonline.com.
[60] Wang, Y., et al. (2018). The application of omics technologies in traditional Chinese medicine research: A review. Journal of Ethnopharmacology, 223, 1–12.
[61] Wang, Y., et al. (2016). Traditional Chinese medicine in the 21st century: A perspective on its development and modernization. The American Journal of Chinese Medicine, 44(2), 221-236.
[62] Wang, M., Su, C., & Ke, C. (2002). Morinda citrifolia: A comprehensive review on its chemical composition and bioactive compounds. Journal of Ethnopharmacology, 80(1), 1-18.
[63] Widyowati, R., & Agil, M. (2018). A review on Zingiberaceae family plants for the development of anti-inflammatory drugs. Asian Pacific Journal of Tropical Biomedicine, 8(2), 53-61.
[64] Wijanarko, M. (2023). Djampi Oesodo as Indonesian Traditional Medicine Philosophy. Journal of Advanced Research in Social Sciences and Humanities, 10(1), 1-8.
[65] Wu, H., et al. (2019). Dragon fruit: A review of its nutritional and health benefits. Journal of Food Science and Technology, 56(1), 1-13.
[66] Yodkeeree, S., Sung, B., & Limtrakul, P. (2015). Molecular mechanisms of curcuminoids: A review. Current Drug Metabolism, 16(5), 325-334.
[67] Zoetmulder, P. J. (1974). Kalangwan: A Survey of Old Javanese Literature. Martinus Nijhoff.
[68] Zhu, W., et al. (2013). Andrographolide inhibits inflammatory cytokines in LPS-activated murine macrophages. Journal of Ethnopharmacology, 148(1), 325-332. https://doi.org/10.1016/j.jep.2013.04.032
[69] Zulfa, R. E., & Suparmi, S. (2024). Analisis Konsep Jamu dalam Relief Candi Borobudur dan Relevansinya dengan Pengetahuan Modern. Jurnal Arkeologi, 15(1), 1-15.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Jurnal Sains dan Kesehatan
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Most read articles by the same author(s)
- Jeane Rose Christine, Hajrah, Fajar Prasetya, Pengaruh Konsumsi Pemanis Buatan Rendah Kalori Sukralosa dan Glikosida Steviol Terhadap Kadar Glukosa Darah Pasien Pengidap Diabetes Melitus Tipe 2 , Jurnal Sains dan Kesehatan: Vol. 4 No. 2 (2022): J. Sains Kes.
- Fajar Prasetya, M Arifuddin, Arsyik Ibrahim, Identifikasi Senyawa Marker Dominan Ekstrak Daun Sirih Hitam dan Kuantifikasi Berdasarkan Perbedaan Lokasi Tanam , Jurnal Sains dan Kesehatan: Vol. 3 No. 2 (2021): J. Sains Kes.
- Novia Dwi Ribatul, Fajar Prasetya, Satriani Badawi, Pengaruh Pemberian Teh Kulit Buah Salak (Salacca zalacaa) Terhadap Kadar Glukosa Darah Mencit yang di Induksi Aloksan , Jurnal Sains dan Kesehatan: Vol. 5 No. SE-1 (2023): Spesial Edition J. Sains Kes.
- Oktaviany Triana, Fajar Prasetya, Hadi Kuncoro, Laode Rijai, Aktivitas Antijamur Ekstrak Daun Ketepeng Cina (Cassia alata L.) , Jurnal Sains dan Kesehatan: Vol. 1 No. 6 (2016): J. Sains Kes.
- Risna Agustina, Abdul Mun’im, Gemini Alam, Azminah Azminah, Angga Cipta Narsa, Hadi Kuncoro, M. Arifuddin, Wisnu Cahyo Prabowo, Noor Linda Febrianie, Erwin Samsul, Iswahyudi Iswahyudi, Islamudin Ahmad, Aktivitas Hemaglutinasi dan Identifikasi Ekstrak Berbasis Green Solvent dari Akar Tapak Dara (Vinca rosea) dan Daun Kadamba (Mitragyna speciosa Korth. Havil) Menggunakan FTIR-Kemometrik , Jurnal Sains dan Kesehatan: Vol. 4 No. 5 (2022): J. Sains Kes.
- Sekar Ningrum, Dewi Rahmawati, Fajar Prasetya, The Effect of Provision Decoged Leaves of Moringa, Red Ginger, Turmeric, Red Meniran, Cinnamon, and Sambiloto Towards Reduction of Blood Pressure in The Region Long Kali District, Paser Regency , Jurnal Sains dan Kesehatan: Vol. 4 No. SE-1 (2022): Spesial Edition J. Sains Kes.
- Aji Yudha Wijaya, Muhammad Amir Masruhim, Hadi Kuncoro , Aktivitas Antiinflamasi Ekstrak Daun Tembelekan (Lantana camara Linn) Pada Tikus Putih (Rattus norvegicus) , Jurnal Sains dan Kesehatan: Vol. 1 No. 6 (2016): J. Sains Kes.
- Nurhidayati Febriana, Fajar Prasetya, Arsyik Ibrahim, Aktivitas Antimikroba Ekstrak Daun Bungur (Langerstroemia speciosa (L.) Pers) , Jurnal Sains dan Kesehatan: Vol. 1 No. 2 (2015): J. Sains Kes.
- Nadia Rahma Kusuma Dewi, Hadi Kuncoro, Laode Rijai, Potensi Sitotoksik Ekstrak Air Daun Sirih Hitam (Piper sp.) , Jurnal Sains dan Kesehatan: Vol. 1 No. 1 (2015): J. Sains Kes.
- Mira Susanti, Hadi Kuncoro, Laode Rijai, Uji Aktivitas Larvasida Ekstrak Daun Keladi Birah (Alocasia indica Schott) Terhadap Larva Nyamuk Culex sp. , Jurnal Sains dan Kesehatan: Vol. 1 No. 1 (2015): J. Sains Kes.
Similar Articles
- Yuspian Nur, Anom Cahyotomo, Nanda, Nurikhsan Fistoro, Profil GC-MS Senyawa Metabolit Sekunder dari Jahe Merah (Zingiber officinale) dengan Metode Ekstraksi Etil Asetat, Etanol dan Destilasi , Jurnal Sains dan Kesehatan: Vol. 2 No. 3 (2020): J. Sains Kes.
- Iqlima Ayu Prestisya, Carellila Kristanto, Fikria Marfuatin Nur, Pemanfaatan Tanaman Andong Merah (Cordyline Fruticosa Linn.) dalam Formulasi Hydrogel Berbasis Starch-Gelatin Sebagai Kombinasi Polimer Alami Alternatif untuk Bentuk Sediaan Jamu , Jurnal Sains dan Kesehatan: Vol. 6 No. 2 (2025)
- Riga Riga, Mauline Adia Silvani, Wandi Oktria, Edi Nasra, Desy Kurniawati, Dewi Meliati Agustini, Jamur Endofitik BJS-3 Asosiasi Sambiloto (Andrographis paniculata): Skiring Fitokimia dan Aktivitas Antioksidan , Jurnal Sains dan Kesehatan: Vol. 5 No. 5 (2023): J. Sains Kes.
- Asrianto Asrianto, Suarna Samai, Muhamad Sahidin, Indra Taufik Sahli, Risda Hartati, Wiwiek Mulyani, Efikasi Biolarvasida Berbagai Tanaman Untuk Pengendalian Vektor Nyamuk Anopheles , Jurnal Sains dan Kesehatan: Vol. 5 No. 2 (2023): J. Sains Kes.
- Jumarti Suhaela, Mirfaidah Nadjamuddin, Muh Ikhsan Amar, Wahyuni Wahyuni, Formulasi dan Uji Aktivitas Antioksidan dan SPF (Sun Protection Factor) Serum Ekstrak Etanol Kulit Pisang Raja (Musa paradisiaca L) , Jurnal Sains dan Kesehatan: Vol. 5 No. 6 (2023): J. Sains Kes.
- Abdul Rahim, Yuyun Febriani, Muhlisun Azim, Nur Rezky Khairun Nisaa, Uji Perbandingan Antioksidan dari Produk Teh Daun Kelor, Teh Bunga Roselladan Teh Daun Melati dengan Metode Seduhan Suhu Konstan , Jurnal Sains dan Kesehatan: Vol. 5 No. SE-1 (2023): Spesial Edition J. Sains Kes.
- Laode Rijai, Reviuw Beberapa Bioaktivitas dan Senyawa Kimia Organisme Laut untuk Kefarmasian , Jurnal Sains dan Kesehatan: Vol. 2 No. 1 (2019): J. Sains Kes.
- Usman Usman, Senyawa Triterpenoid dari Kulit Batang Melochia umbellata dan Bioaktivitasnya , Jurnal Sains dan Kesehatan: Vol. 2 No. 4 (2020): J. Sains Kes.
- Claudius Hendraman B. Tobi, Mustika Endah Pratiwi, Identifikasi Senyawa Flavonoid dan Uji Aktivitas Antibakteri Ekstrak Terpurifikasi Daun Beluntas (Pluchea Indica L.) terhadap Staphylococcus aureus , Jurnal Sains dan Kesehatan: Vol. 5 No. 5 (2023): J. Sains Kes.
- Usman, Potensi Senyawa Metabolit Sekunder Dari Kulit Batang Melochia umbellata (Houtt) Stapf var. degrabrata paliasa) Sebagai Anti-Tuberkulosis , Jurnal Sains dan Kesehatan: Vol. 1 No. 4 (2015): J. Sains Kes.
You may also start an advanced similarity search for this article.
Make a Submission
Sertifikat Akreditasi
