Aktivitas Antimikroba Ekstrak Daun Karamunting (Melastoma malabathricum L.) Terhadap Bakteri Penyebab Diare

Authors

  • Nataniel Tandirogang Fakultas Kedokteran Universitas Mulawarman Samarinda Kalimantan Timur Author
  • Swandari Paramita Fakultas Kedokteran Universitas Mulawarman Samarinda Kalimantan Timur Author
  • Yadi Yasir Fakultas Kedokteran Universitas Mulawarman Samarinda Kalimantan Timur Author
  • Yuniati Yuniati Fakultas Kedokteran Universitas Mulawarman Samarinda Kalimantan Timur Author
  • Meiliati Aminyoto Fakultas Kedokteran Universitas Mulawarman Samarinda Kalimantan Timur Author
  • Evi Fitriany Fakultas Kedokteran Universitas Mulawarman Samarinda Kalimantan Timur Author

Keywords:

Melastoma malabathricum, aktivitas antimikroba, disc diffusion method, minimum inhibitory concentration

Abstract

Diare hingga kini masih merupakan masalah kesehatan utama di Indonesia. Pemberian antibiotik merupakan salah satu upaya penatalaksanaan diare, namun belakangan terkendala masalah adanya resistensi terhadap antibiotik. Berdasarkan hal tersebut, maka upaya pencarian sumber antimikroba baru berbasis tumbuhan obat perlu dilakukan. Penelitian ini dilakukan untuk menguji potensi ekstrak daun karamunting (Melastoma malabathricum L.) yang secara tradisional digunakan etnis Dayak sebagai obat diare. Aktivitas antimikroba ekstrak tumbuhan diuji terhadap 5 bakteri standar;  Escherichia  coli ATCC 35128, Shigella sonnei ATCC 25931, Campylobacter jejuni ATCC 33291, Pseudomonas aeruginosa ATCC 15442, dan Enterobacter cloacae ATCC13047. Pengukuran aktivitas antimikroba dilakukan dengan disc diffusion method (Kirby-Bauer) dan pengukuran minimum inhibitory concentration (MIC). Hasil penelitian menunjukkan ekstrak daun M. malabathricum dapat menghambat pertumbuhan seluruh bakteri uji, dengan diameter zona hambat sebesar 12,3-16 mm dan MIC sebesar 2,3-13,3 mg/ml. Kesimpulan penelitian ini adalah ekstrak daun M. malabathricum berpotensi sebagai antidiare berdasarkan aktivitas antimikrobanya.  

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Published

2024-11-01

Issue

Vol. 1 No. 7 (2017): J. Sains Kes.

Section

Articles

How to Cite

[1]
N. Tandirogang, S. Paramita, Y. Yasir, Y. Yuniati, M. Aminyoto, and E. Fitriany, “Aktivitas Antimikroba Ekstrak Daun Karamunting (Melastoma malabathricum L.) Terhadap Bakteri Penyebab Diare”, J. Sains. Kes, vol. 1, no. 7, pp. 345–351, Nov. 2024, Accessed: Dec. 20, 2025. [Online]. Available: https://jsk.ff.unmul.ac.id/index.php/JSK/article/view/121

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