Efek Pemberian Gel Ekstrak Etanol Daun Ekor Naga (Rhaphidophora pinnata (L.f) Schott) sebagai Antiinflamasi Metode CarrageenanInduced Air Pouch

The Effect of Administering Ethanolic Extract Gel from Ekor Naga(Rhaphidophora pinnata (L.f) Schott) Leaves as an Anti-InflammationCarrageenan-Induced Air Pouch Method

Authors

  • Fathnur Sani K Program Studi Farmasi, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi, Indonesia Author
  • Kristin Simamora Program Studi Farmasi, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi, Indonesia Author
  • Havizur Rahman Program Studi Farmasi, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi, Indonesia Author
  • Ave Olivia Rahman Program Studi Kedokteran, Fakultas Kedokteran dan Ilmu Kesehatan, Universitas Jambi, Indonesia Author
  • Yuliawati Yuliawati Program Studi Farmasi, Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi, Indonesia Author

DOI:

https://doi.org/10.30872/jsk.v5i5.426

Keywords:

Daun Ekor Naga, Gel, Inflamasi, Air Pouch

Abstract

Ekstrak etanol daun ekor naga  (Rhaphidophora pinnata (L.f) Schott) telah diteliti memiliki efek sebagai agen antiinflamasi. Penenlitian ini bertujuan untuk memformulasi sediaan topikal gel ekstrak daun ekor naga sehingga dapat menjadi menjadi langkah lanjut dari penelitian sebelumnya sebagai upaya pengembangan produk. Metode penelitian yang digunakan adalah experimental design. Kelompok perlakuan dibagi menjadi lima kelompok yaitu: Kontrol positif (Hidrokortisone), Formula 0 (Basis Gel), Formula 1 (Konsentrasi Ekstrak 10%), Formula 2 (Konsentrasi Ekstrak 15%), dan Formula 3 (Konsentrasi Ekstrak 20%). Hewan uji yang digunakan masing-masing kelompok perlakuan 5 ekor. Data yang didapat dianalisis menggunakan ANOVA satu arah dengan tingkat kepercayaan 95%. Hasil penelitian menunjukkan bahwa semakin banyak ekstrak maka semakin baik efek antiinflamasinya. Namun berdasarkan data evaluasi sediaan pada penelitian sebelumnya tentang formulasi gel maka disimpulkan bahwa formula 2 merupakan formula terbaik dengan efek yang secara statistic hampir sama dengan formula 3 serta memiliki stabilitas gel yang baik dalam formulasi.

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Published

2024-11-15

Issue

Vol. 5 No. 5 (2023): J. Sains Kes.

Section

Articles

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How to Cite

[1]
F. S. . K, K. . Simamora, H. . Rahman, . A. O. . Rahman, and Y. Yuliawati, “Efek Pemberian Gel Ekstrak Etanol Daun Ekor Naga (Rhaphidophora pinnata (L.f) Schott) sebagai Antiinflamasi Metode CarrageenanInduced Air Pouch: The Effect of Administering Ethanolic Extract Gel from Ekor Naga(Rhaphidophora pinnata (L.f) Schott) Leaves as an Anti-InflammationCarrageenan-Induced Air Pouch Method”, J. Sains. Kes, vol. 5, no. 5, pp. 576–583, Nov. 2024, doi: 10.30872/jsk.v5i5.426.

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