Total Fenolik, Flavonoid, dan Aktivitas Antioksidan Ekstrak dan Fraksi Eceng Gondok (Eichhornia crassipes (Mart.) Solms)

Total Phenolic, Flavonoid, and Antioxidant Activity of Water Hyacinth Extract and Fraction (Eichhornia crassipes (Mart.) Solms)

Authors

  • Aptika Oktaviana Trisna Dewi Program Studi Farmasi, Politeknik Indonusa Surakarta, Indonesia Author https://orcid.org/0009-0000-8771-6535
  • Adnan Nur Avif Program Studi Farmasi, Politeknik Indonusa Surakarta, Indonesia Author

DOI:

https://doi.org/10.30872/jsk.v5i2.p132-139

Keywords:

antioksidan, eceng gondok, fenolik, flavonoid

Abstract

Eceng gondok merupakan gulma air yang sangat cepat pertumbuhannya. Keberadaannya di perairan mengakibatkan kerugian yang besar bagi lingkungan, sosial maupun ekonomi. Namun di sisi lain, eceng gondok memiliki kandungan senyawa aktif flavonoid, alkaloid, steroid, terpenoid, antosianin, tannin, fenolik, antraquinon dan quinon. Senyawa tersebut dapat dimanfaatkan sebagai agen antioksidan, antibakteri, antifungi, antitumor, antikanker, antikoroner dan antiinflamasi. Tujuan penelitian ini adalah mengetahui kadar fenolik dan flavonoid pada ekstrak dan fraksi tanaman eceng gondok serta nilai IC50 yang menggambarkan efektivitas antioksidannya. Ekstrak diperoleh dengan maserasi menggunakan etanol 96%. Fraksinasi terhadap ekstrak etanol eceng gondok menggunakan pelarut n-heksana, etil asetat dan air. Pengujian antioksidan menggunakan metode DPPH. Hasil uji flavonoid pada ekstrak etanol yaitu 0,023±0,0015gEQ/g, fraksi etil asetat 0,028±0,0015gEQ/g, fraksi n-heksana 0,008±0,0005gEQ/g, dan fraksi air 0,002±0,0005gEQ/g. Hasil uji kadar fenolik herba eceng gondok pada ekstrak etanol sebesar 5,403 ± 0,910mgGAE/g, fraksi etil asetat sebesar 1,810 ± 0,225mgGAE/g, fraksi n-heksana sebesar 0,457 ± 0,290mgGAE/g dan fraksi air adalah sebesar 0,147 ± 0,151mgGAE/g. Nilai IC50 untuk ekstrak etanol sebesar 48,64 mg/mL, fraksi etil asetat sebesar 223,27 mg/mL, fraksi air 451,86 mg/mL, fraksi n-heksana 845,00 mg/mL.

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Published

2025-01-14

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Vol. 5 No. 2 (2023): J. Sains Kes.

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How to Cite

[1]
A. O. T. . Dewi and A. N. . Avif, “Total Fenolik, Flavonoid, dan Aktivitas Antioksidan Ekstrak dan Fraksi Eceng Gondok (Eichhornia crassipes (Mart.) Solms): Total Phenolic, Flavonoid, and Antioxidant Activity of Water Hyacinth Extract and Fraction (Eichhornia crassipes (Mart.) Solms)”, J. Sains. Kes, vol. 5, no. 2, pp. 132–139, Jan. 2025, doi: 10.30872/jsk.v5i2.p132-139.

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