Isolasi, Karakterisasi, dan Uji Aktivitas Antioksidan Senyawa Turunan Kuersetin dari Kulit Batang Melicope quercifolia

Abror Rahman; Ifana Mahardika; Ratih Dewi Saputri; Tjitjik Srie Tjahjandarie; Mulyadi Tanjung

Penulis

Abror Rahman Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga Penulis
Ifana Mahardika Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga Penulis
Ratih Dewi Saputri Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga Penulis
Tjitjik Srie Tjahjandarie Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga Penulis
Mulyadi Tanjung Natural Products Chemistry Research Group, Organic Chemistry Division, Department of Chemistry, Faculty of Science and Technology, Universitas Airlangga Penulis

Kata Kunci:

Melicope quercifolia, pakipodol, ayanin, antioksidan

Abstrak

Dua senyawa turunan kuersetin, pakipodol (1) dan ayanin (2) telah diisolasi dari kulit batang Melicope quercifolia (B.S. William) Ridl. Struktur kedua senyawa turunan kuersetin ditetapkan berdasarkan analisis spektroskopi UV, IR, MS dan NMR. Uji aktivitas antioksidan senyawa 1–2 terhadap radikal DPPH memperlihatkan IC50 254 ± 10 dan 38,55 ± 0,02 μg/mL.

Referensi

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